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Scientists Study How Low Blood Sugar in Babies Affects Brain Development

June 1, 2026 · Nature

Researchers tracked nearly-full-term babies to see if early sugar problems cause learning delays later.

Scientists in New York studied babies who were born a few weeks early to see if low blood sugar right after birth could hurt their brain development. The researchers followed these babies for nearly two years to check how well they learned and grew. They wanted to find out if babies who had low blood sugar in their first day of life would have brain development problems later. This study is important because many babies are born with this condition, and doctors need to know the best ways to help them.

The study took place at four hospitals in New York from 2021 to 2024. The hospitals were in the Bronx and Westchester County, and they served families from many different backgrounds. Some families had public insurance while others had private insurance. The researchers picked these hospitals because they wanted to study babies from all kinds of families.

The scientists focused on babies born between 35 and 37 weeks of pregnancy. Normal pregnancy lasts about 40 weeks, so these babies were born a little early. The babies also had to weigh more than 4.4 pounds to be part of the study. Doctors tested these babies' blood sugar levels during their first 24 hours of life to see which ones had problems.

Low blood sugar, called hypoglycemia, happens when a baby's body doesn't have enough sugar in the blood. This can be dangerous because the brain needs sugar to work properly. In the study, doctors said blood sugar was too low if it dropped below certain levels during the baby's first day. Some babies had this problem once, while others had it happen several times.

When the babies grew to be 18 to 24 months old, the researchers brought them back for special tests. These tests checked how well the children could think, talk, move, and get along with others. The tests were like games and activities that showed how the children's brains were developing. The people giving the tests didn't know which babies had low blood sugar problems when they were born.

Scientists wanted to find out if babies who had low blood sugar in their first day of life would have brain development problems later.

Comprehension quiz preview

1. How long did the researchers follow the babies to check their development?

  • A6 months
  • BNearly two years
  • C5 years
  • D1 year

2. At what age did normal pregnancy usually end according to the article?

  • A35 weeks
  • B37 weeks
  • CAbout 40 weeks
  • D42 weeks

3. How many hospitals in New York were part of this study?

  • ATwo
  • BThree
  • CFour
  • DFive

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